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OXYCONTIN 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg are only for use in patients in whom tolerance to an opioid of comparable potency has been establish.
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In high doses, or in some persons not tolerant to opioids,
Further, Chronic use of oxycodone (particularly with higher doses) often causes concurrent hypogonadism or hormone imbalance.
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